There are no real differences beyond those arising from differences in aperture and focal length. For example, here are two very similar shots, one shot on a DX format DSLR and the other shot on 4x5 film:

https://drive.google.com/open?id=0B4v6yNyRkl5uUThuRm9tVWhGNU...

https://drive.google.com/open?id=0B4v6yNyRkl5ua1BlMzNHVlRUUH...

The one exception would be movements: most 4x5 cameras can do tilt and shift, whereas tilt/shift lenses for DSLRs are very expensive and specialist.